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Downtown LA Office Vacancy Hits 28.1%; GenCure Leases 120K SF
Development

Downtown LA Office Vacancy Hits 28.1%; GenCure Leases 120K SF

2026-05-14Development

Downtown LA's Class A office vacancy climbed to 28.1% in Q1 2026. Meanwhile, the life sciences sector saw a boost with biotech firm GenCure leasing 120,000 SF at 5500 Wilshire Blvd. Industrial rents in the Inland Empire also surged 6.2% year-over-year.

SUBJECT LINE: Quick Hits Dominate as LA Market Digests Data

PREVIEW TEXT: Today's newsletter is a rapid-fire download of critical market intel and quick hits from across LA.

LA Development Insider

Thursday, May 14, 2026 | LA Development Intelligence

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QUICK HITS

  • LAX Expansion: LAWA confirms Phase 2 of the LAX Capital Improvement Program is on track for 2028 completion, with $5.5 billion allocated for new terminals and ground transport. (LAWA)
  • Office Vacancy: Downtown LA Class A office vacancy hits 28.1% in Q1 2026, a 150 basis point increase from Q4 2025, per CBRE. (CBRE)
  • Industrial Rents: Average asking rents for industrial space in the Inland Empire surged 6.2% year-over-year to $1.98/SF NNN in Q1 2026. (JLL)
  • Multifamily Starts: New multifamily housing starts in LA County dropped 12% in Q1 2026 compared to Q1 2025, totaling 3,200 units. (Dodge Analytics)
  • Hotel Performance: LA County hotel occupancy averaged 71% in April 2026, up from 68% in March, but ADR remains flat at $225. (STR)
  • Retail Investment: Retail investment sales volume in LA County fell 22% year-over-year in Q1 2026, with cap rates widening by 50 basis points on average. (Newmark)
  • Life Sciences Growth: Biotech firm GenCure leases 120,000 SF at 5500 Wilshire Blvd, marking one of the largest life sciences deals this year. (Cushman & Wakefield)
  • Infrastructure Bill: State Senate Bill 789, aimed at streamlining environmental review for transit-oriented developments, passed the Assembly committee and moves to a full vote next month. (CA Legislature)
  • Housing Affordability: The median home price in LA County reached $920,000 in April, up 3% month-over-month, exacerbating affordability concerns. (California Association of Realtors)
  • Construction Costs: Construction material costs in Southern California increased 1.8% in Q1 2026, primarily driven by steel and concrete prices. (Turner Construction)
  • WHY THIS MATTERS

    Today's quick hits paint a picture of a nuanced, yet challenging, LA market. While industrial rents continue their upward trajectory and the life sciences sector shows resilience with significant leases like GenCure's, the office market remains in a deep slump. Developers and investors should note the continued decline in multifamily starts and widening retail cap rates, suggesting a cautious approach to new speculative projects in those sectors. The push for streamlined transit-oriented development via SB 789 could offer future opportunities, but current conditions demand sharp pencils and strategic positioning.

    Intelligence sourced from 15+ LA real estate feeds. Published daily by ABR Media Group | ladevinsider.com

    SUMMARY: Downtown LA's Class A office vacancy climbed to 28.1% in Q1 2026. Meanwhile, the life sciences sector saw a boost with biotech firm GenCure leasing 120,000 SF at 5500 Wilshire Blvd. Industrial rents in the Inland Empire also surged 6.2% year-over-year.

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